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Demarquoy J, Le Borgne F
Propionate, produced by Akkermansia, has been shown to reduce activity in brain reward centers associated with high-calorie food cravings in human functional MRI studies
GLP-1 agonists is currently approved as second/third-line therapy for T2DM patients with inadequate glycaemic control (HbA1c 7.0 or 53 mmol/mol) despite lifestyle modifications and first-line antihyperglycaemics (metformin/sulfonylurea/insulin)
Zhang W, Lian Y, Li Q, Sun L, Chen R, Lai X, Sun S (2020) Preventative and therapeutic potential of flavonoids in peptic ulcers
High-bioavailability supplements can help bridge that gap more effectively
This differs from the general malaise of medication adjustment, which typically improves within 2-4 weeks
