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Interconnection between cardiovascular, renal and metabolic disorders: a narrative review with a focus on Japan

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The good news is that severe side effects are very rare, including joint and muscle aches and pains, numbness, and swelling

Studies have found that the longer cellular damage is allowed to occur, the more cellular function is impaired, giving way to the accumulation of even more damaged cells and accelerated aging

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Overview of the Phase 2 NEJM Trial Design and Participants The phase 2 trial was a randomised, double-blind, placebo-controlled, dose-ranging study enrolling 338 adults with obesity or overweight without type 2 diabetes, assessing retatrutide doses of 1 mg, 4 mg, 8 mg, and 12 mg over 48 weeks