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Start your intake The Rebound Weight Gain Phenomenon: What Research Shows Weight regain after stopping GLP-1 medications is well-documented and occurs because the medication's appetite-suppressing effects cease
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Both the high intensity test and training protocols were adapted from published protocols 69,70
The decline is normal, but its effects accumulate: less deep sleep triggers less overnight GH release, which further reduces muscle maintenance, which shifts body composition toward higher fat percentage, which further suppresses GH through somatostatin signaling
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When constipation is addressed early and thoughtfully, patients are more likely to stay on therapy and achieve lasting benefits for weight and metabolic health
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