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It acts as an inhibitor of nicotinamide N-methyltransferase (NNMT), a crucial enzyme involved in energy metabolism and fat storage

AT immune cells also secrete pro-inflammatory cytokines and other pro-inflammatory products into the systemic circulation, which affect the entire body, thus representing a key factor in the transition from simple obesity to cardiovascular disease, type II diabetes, and related metabolic disorder complications (130)

Stimulates blood flow: Stimulates the growth of new blood vessels (angiogenesis) to supply oxygen and nutrients to damaged tissues

Mechanisms that do not share monoamine transporter targets

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