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Structurally, it shares 94% sequence homology with human GLP-1 but includes two critical modifications: the substitution of amino acids to prevent enzymatic degradation by Dipeptidyl Peptidase-4 (DPP-4), and the addition of a C-18 fatty di-acid side chain
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The remaining 60 to 70% feel minimal or no change
Disruptions in these signals can lead to issues such as obesity and metabolic syndrome
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