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Infiltrating immune cells contribute to a feed-forward loop of inflammation and oxidative stress (Fischer and Maier, 2015)

Reactivity of hydrogen sulfide with peroxynitrite and other oxidants of biological interest

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It naturally occurs in the body, is mostly produced in the liver and its primary purpose is to counteract toxins and reduce oxidative stress

Biologics are generally well represented across Phase I to Phase III, with peptide-based drugs among the most numerically dominant at each stage (Figure 3 b)

The Side-Effect Conversation This is where the two compounds diverge most sharply