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Patients that maintained treatment response for 2 weeks at the end of the open label treatment period were eligible to be randomized to ongoing treatment with the same dose of VYVANSE (N=78) or switched to placebo (N=79) during the double-blind phase

M., Economopoulos, V., & Mirmirani, P

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doi:10.1016/j.tox.2022.153136

Distinguishing the source requires careful observation and sometimes trial periods where one variable is adjusted at a time