Severe vitamin B12 deficiency can lead to memory loss, joint pain, and vision problems, among other complications
doi: 10.3389/fphar.2025.1543870 Received 12 December 2024 Accepted 25 March 2025 Published 14 May 2025 Volume 16 - 2025 Edited by Sabrina Petralla, Heidelberg University, Germany Reviewed by Yuan Wei, Jiangsu University, China Shameer Pillarisetti, University of Studies G
Patient Reported Outcomes Patients rated the degree of distress associated with their belly appearance on a 9-point rating scale that was then transformed to a score from 0 (extremely upsetting and distressing) to 100 (extremely encouraging)
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Simultaneously, insulin resistance, up- and downregulation of vessel GLUT and increased BBB permeability drive systemic hyperglycemia and reduced utilization of glucose at the cellular level [38, 58, 61]
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