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The tablet should be removed carefully from its packaging and immediately placed under the tongue, where it will dissolve within thirty to sixty seconds without the need for water

Contact your GP or diabetes care team if you experience any of the following: Persistent or worsening fatigue that continues beyond the first 46 weeks of treatment or does not improve with dietary and lifestyle modifications Severe tiredness that significantly impairs your ability to perform daily activities, work, or care for yourself Symptoms suggestive of hypoglycaemia , particularly if occurring frequently or if you are unable to maintain blood glucose levels within target range Signs of dehydration or electrolyte imbalance , including dizziness, reduced urine output, dark urine, persistent headaches, or muscle cramps Concurrent symptoms such as unexplained weight loss beyond expected targets, persistent nausea or vomiting preventing adequate nutrition, or palpitations Mood changes including low mood, anxiety, or depression, which can both cause and be exacerbated by fatigue Snoring, witnessed pauses in breathing during sleep, or excessive daytime sleepiness , which may indicate obstructive sleep apnoea, a treatable condition common in people with obesity [19] Seek urgent medical attention (call 999 or go to A&E) if you experience severe chest pain, shortness of breath, or severe, persistent abdominal pain (especially if radiating to the back), as these could indicate serious conditions including pancreatitis, which is a rare but recognised complication of GLP-1 treatment

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Glucagon-like peptide-1 (GLP-1) agonists are medications used to help individuals with Type 2 Diabetes (T2DM) and obesity

1 Introduction Cardiovascular disease (CVD) continues to be a significant global health concern, with ischemic stroke and acute myocardial infarction ranking as the second and third leading causes of death worldwide in 2019 ( The complex interaction between diabetes mellitus (DM) and cardiovascular events complicates patient management

Surgical Complications : Ozempic use may elevate the risk of complications during surgical procedures, particularly due to its impact on gastric emptying