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Positioning in guidelines NICE NG28 advocates the use of SGLT2 inhibitors as second-line pharmacotherapy in addition to metformin for people who have established cardiovascular disease (CVD) or have a high risk of CVD (QRISK 10%)

Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors

Symptoms such as facial swelling, lip or tongue swelling, breathing difficulties, or a rapidly spreading rash require urgent medical attention

PubMed laboratory research record [PMID: 19686418] PubMed record related to this compound for laboratory literature review

This may be especially important to monitor if you have diabetes, which is why Makhija recommends monitoring your blood sugar levels and consulting your prescribing physician

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