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Assessed 10 May 2021
The pattern is explainable: The people experiencing transformative outcomes are the ones whose obesity was being driven primarily by the mechanisms GLP-1 actually targets: inflammation, gut signaling, neurological dysregulation
Those issues can create competing explanations
Bradbury JA, Danjoux JP, Voller J, Spencer M, Brocklebank T (1991) A randomised placebo-controlled trial of topical cysteamine therapy in patients with nephropathic cystinosis
High doses may cause overstimulation or irritability
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