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Current clinical guidance strongly discourages their use

The use of nutritional supplements to induce ketosis and reduce symptoms associated with keto-induction: a narrative review

For example, single-cell transcriptomics has enabled researchers to map the trajectory of programmatic reorganization and identify new intermediate cell populations

Additional context on medical indications and off-label questions is provided in our article on indications and off-label use for weight loss medications, even though naltrexone/bupropion itself does not belong to the group of GLP-1 agonists

Understanding its mechanisms and effects is crucial for patients considering or currently using this medication