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Tirzepatide is not a shortcut or a stand-alone solution

For someone on a GLP-1 whose appetite is suppressed, this requires planning rather than relying on hunger cues

With adequate protein intake and consistent resistance training, research shows that muscle loss can be minimised and strength preserved, even during rapid weight loss

The other 40% either cycle between periods on and off medication, or attempt lifestyle maintenance alone

Understanding an individual's genetic, dietary, and microbiome profiles could improve the effectiveness of these interventions and minimize the potential adverse effects of these treatments

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