Zamora, R., Vodovotz, Y
The Science is Clear: Exercise Still Matters GLP-1 meds for weight loss work, they dont replace everything
Classical pro-inflammatory cytokines (IL1B, IL6, TNF) and pattern recognition receptors (TLR2, TLR4) are markedly increased, along with adhesion molecules (VCAM1, ICAM1) and chemokines (CCL2, CXCL8) that promote leukocyte recruitment and vascular injury (Falco-Holanda et al., 2021
Similar results were also observed in humans
Importantly, any patch claiming to contain actual semaglutide, liraglutide, or other GLP-1 receptor agonists would be an unapproved, potentially illegal drug product in the US
While neither liraglutide nor semaglutide is FDA-approved for cardiovascular protection, research suggests both may help lower the risk of major heart-related events like heart attack, stroke, or cardiovascular death in people with type 2 diabetes