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10.1371/journal.pntd.0008709 27 GagliardiM.CotellaD.SantoroC.CorD.BarlevN

The company describes its facilities as GMP-certified per its published materials

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While this is far from proven, it is a significant scientific clue worth following

Metformin may produce modest weight loss of 4-7 pounds over 6-12 months in patients with Hashimoto's who have concurrent insulin resistance or prediabetes, though it is not FDA-approved for this indication