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This peripheral inflammation is a known driver of neuroinflammation, which is implicated in mood disorders, cognitive decline, and neurodegenerative diseases

doi: 10.1006/gcen.1997.6881 48 HolmesRLBallJN

But they do create an environment where additional support may prove valuable

I started with too low of a dose as I have used a semiglutide for 1 year prior to changing