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Consistent with this, KEGG pathway analysis revealed downregulation of -oxidation in KO mice, accompanied by upregulation of glycolysis and mitochondrial oxidative phosphorylation, reflecting a systemic shift in fuel preference toward carbohydrates driven by carnitine depletion and impaired fatty acid oxidation
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In rare cases, switching to Microdose GLP-1 Protocol (starting at $129/mo) may reduce side effects while maintaining therapeutic benefit, though this requires individualized assessment
PlexusDx recommends coordinating with your primary care provider or endocrinologist to review thyroid labs quarterly during the first year of GLP-1 therapy
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