Liakos A, Karagiannis T, Athanasiadou E, Sarigianni M, Mainou M, Papatheodorou K, et al
For the study, which was published in the journal Molecular and Cellular Neuroscience , researchers reviewed findings from 30 preclinical studiesmostly on animals and cellsthat looked at the impact on signs of Alzheimers disease of four GLP-1 receptor agonists: liraglutide (Victoza, Saxenda), semaglutide (Ozempic, Wegovy), exenatide (Byetta), and dulaglutide (Trulicity)
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Semaglutide targets only the GLP-1 receptor and achieved 14.9% mean weight loss at 68 weeks in the STEP 1 trial