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More eumelanin = bigger hats

HEK293 C24 cells stably expressing the H188 FRET reporter were obtained by G418 selection and grown in monolayers to 70% confluency in 100 cm 2 tissue culture dishes and were then transfected with plasmids (11 g/dish) encoding human GLP-1R, human Y2-R, or human Y1-R

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It likely means you need a higher dose to cross your individual response threshold, which is exactly what the escalation schedule is designed to achieve

however, the natural hormone disappeared from the body within minutes

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