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Importantly, eukaryotic cells also contain an enzyme called catalase to specifically neutralize hydrogen peroxide [1, 8, 9]
PMID 26177183
Obtaining sufficient systemic exposure of peptide-based drugs following oral administration is difficult owing to the acidic environment and presence of proteolytic enzymes in the stomach, and the limited permeability of peptides and proteins through the gastrointestinal epithelium [20, 25]
The problem arises when too much homocysteine is available, and it ends up being incorporated into too many proteins
Radel JA, Pender DN, Shah SA
Barba de la Rosa et al., 2022
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