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In the US it is generally recognized as safe (GRAS) with no upper addition limits for standard food use. Triggering GLP-1 production Many nutrients trigger GLP-1 production, but not all have the same response

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For topiramate, the MHRA now requires a Pregnancy Prevention Programme including pregnancy testing before initiation, highly effective contraception throughout treatment, annual specialist review, and a patient guide with risk acknowledgement

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J Am Acad Child Psych

DeVries J