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It's enough to make anyone's head spin
Vitamin B12 injections have long been the only treatment for pernicious anemia
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That is a substantial monotherapy effect for an appetite-axis-only agent, and it established cagrilintide as a credible weight-management candidate on its own
Scores on the Three-Factor Eating Questionnaire (TFEQ-R18) improved in all treatment groups, with Cagrilintide producing greater improvements than placebo in specific domains: cognitive restraint, notably at 1.2 mg and 4.5 mg, emotional eating notably at 0.3 mg and 2.4 mg, and uncontrolled eating notably at 1.24.5 mg
The mean absolute bioavailability observed after IM injections was approximately 14%19% in rats and 45%51% in beagle dogs
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