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It is thought to influence the hypothalamic-pituitary-adrenal (HPA) axis, aiding in stress response regulation by stabilizing blood pressure and reducing stress hormones like cortisol

The FDA approved Mounjaro for that indication in May 2022

Ali, who was also not involved in this review, noted that a problem affecting a lot of research in this area is that it comes out of smaller studies as double-blind controlled studies require a lot of time and monetary investment. Obesity is a multifactorial condition

Wedes SH, Khatri SB, Zhang R, Wu W, Comhair SA, et al: Noninvasive markers of airway inflammation in asthma

For lupus patients, this distinction matters because appetite suppression doesn't require systemic immune activation or additional inflammation

Cost is another factor