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Its not a diet
Meta-analyses show modest but statistically significant weight loss, primarily in overweight or obese adults and people with low baseline carnitine levels (vegans/vegetarians, older adults)
Almost suspiciously simple, depending on your perspective
That philosophy extends to how we discuss their application
Finally, a four-year, multicenter, clinical trial in 421 diabetic patients with distal symmetric sensorimotor polyneuropathy found no difference between oral administration of 600 mg/day of lipoic and placebo on the primary endpoint, a composite score that assessed neuropathic impairment of the lower limbs and nerve conduction (78)
A separate pool of NADP+ is reduced to NADPH primarily through the pentose phosphate pathway and isocitrate dehydrogenase
