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These combined effects make GLP-1 a key player in maintaining healthy blood glucose control and body weight regulation

As a triple agonist targeting GLP-1, GIP, and glucagon receptors simultaneously, retatrutide activates three metabolic pathways where semaglutide activates one and tirzepatide activates two

Appl Microbiol Biotechnol 100:48654873

This may have to do with its interaction with other hormones, such as serotonin (known popularly as the happy hormone), which is a neurotransmitter involved in mood and appetite regulation, and sex hormone-binding globulin (SHBG)

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