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Compound 2 was inactive as a GLP-1R agonist in the unpotentiated cAMP screening assay (SA), which did not include BETP, but demonstrated a 70% effect at 20 M in the presence of BETP (Fig

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doi: 10.1016/j.cmet.2021.01.015, 162 ZhangX

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AOD 9604 has a substantial history of clinical study