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The finding that the loss of GS-E transport increased lipid hydroperoxides, , -unsaturated carbonyls, and glutathione-conjugates of 4HNE were consistent with our predictions from in vitro studies
Quick definition: Glutathione is a tripeptide antioxidant the body synthesizes from three amino acids cysteine, glutamic acid, and glycine
Overload on the kidneys or liver in patients with preexisting conditions
(DPPH 2, 2-diphenyl-1-picrylhydrazyl, is a stable free radical commonly employed to assess antioxidant capacity
Recent B12 administration: Therapeutic injections for deficiency can temporarily raise levels significantly
Levodopa and cobalamin-related neurotoxic metabolites and benefits of COMT inhibitors The breakdown of LDopa through COMT requires methyl group transfer, leading to the formation of the stable compound 3-O-MethylDopa (Mller and Riederer 2023)
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