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Title : Use of GLP1-RAs in patients with a history of cholelithiasis Author: Sarah Hughes, PharmD Candidate 2024 University of Rhode Island, School of Pharmacy Reviewer: Courtney Cameron, PharmD, BCACP Background Cholelithiasis, also known as gallstones, are hardened collections of bile materials such as cholesterol or bilirubin that collect at the bottom of the gallbladder

NLRP3 inflammasome activation through heart-brain interaction initiates cardiac inflammation and hypertrophy during pressure overload

A few hours forgotten on a counter can significantly reduce remaining potency

By promoting cell migration to the site of an injury, it helps the cells that rebuild tissue reach where they are needed

Early clinical research in the 1980s showed that DSIP injections helped some patients with chronic insomnia fall asleep faster and improved sleep architecture

Tirzepatide works for weight loss through a dual-action mechanism targeting the pathways in the body that control both glucose metabolism and appetite