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however, their clearance function in vivo is limited

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Angiogenesis and VEGF Signalling Research indicates BPC-157 may upregulate vascular endothelial growth factor (VEGF) pathways in experimental models, contributing to: Capillary formation Accelerated wound closure Improved microvascular repair Reference: Hsieh et al., 2017 Angiogenic mechanisms in BPC 157-treated tissues PubMed: 3

While frank hyperglycemia is uncommon, those with underlying insulin resistance or diabetes should be monitored for any change in glucose control