ICH Q2(R2) explains general principles for checking whether an analytical method is suitable and reliable
A deficiency or lack of Vitamin B12 is quite common in the over 65s, those diagnosed with pernicious anaemia, and in anyone who follows a vegan, strict vegetarian, or extreme/fad/restricted diet for a long time without taking a B12 supplement or eating fortified foods
Those with adequate levels often experience heightened focus and reduced risk of depression
It can be taken together with CoQ10 for energy, as it simplifies the conversion of the coenzyme with an antioxidant function into its active form to protect cells from damage
This may be explained by several mechanisms by which vitamin B12 indirectly affects heart health, such as reducing the risk of hypertension, lowering homocysteine levels, and regulating the nervous system
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