Real Simple
The Phase 3 Breakthrough On May 21, 2026, Eli Lilly released topline results from TRIUMPH-1, the first registrational Phase 3 obesity trial for Retatrutide
That's a reason to keep on top of your nutrition and strength-training while on these drugs, he writes, "especially for older people like me, who are [already] susceptible to muscle loss." There are people who should steer clear of GLP-1 drugs, Kessler notes, including those with a personal or familial history of certain thyroid and endocrine cancers, those with chronic kidney disease, pancreatitis, inflammatory bowel diseases, uncontrolled diarrhea or constipation or gastroparesis, or if you are pregnant
Baseline renal function matters when evaluating any compound cleared by the kidneys, and is a standard part of any comprehensive pre-intervention assessment
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