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Activation of the renin-angiotensin-aldosterone system (RAAS) and elevated endothelin-1 levels promote vasoconstriction, fluid retention, and increased afterload

Additionally, it can lead to increased muscle mass, accompanied by a decrease in body weight, and reduce physical and mental fatigue

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However, like any treatment, there may be long-term side effects to consider

This led to a theory that GLP-1 may be important for the development of hair follicles