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Most side effects during the first few weeks are gastrointestinal: nausea, constipation, reduced appetite, and occasionally diarrhea
Int J Exp Clin Res
6.5 Key efficacy outcomes of the global trials (PIONEER 18) The key efficacy outcomes of the global PIONEER studies (PIONEER 15 and PIONEER 78) are summarized in Fig
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According to FDA labeling, the injection can be administered in the morning, afternoon, or evening with consistent efficacy
Splitting doses is sometimes considered for managing side effects, but this changes the pharmacokinetic profile and should only be done under guidance
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