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FIGURE 5 Exercise-induced alterations in the expression of oxidative stress marker proteins in GK rat liver and kidney To confirm the defensive effects of exercise on oxidative stress in diabetes, we investigated the expression of stress-sensitive marker proteins in the liver and kidney of control Wistar and GK rats with or without exercise (Figure 6)

In this line, the transcription factor NFE2L2 also seems to strengthen the oxidative stress defense in leukemic cells by regulating the expression of many antioxidative proteins especially in case of additional chemotherapeutic treatment (100, 101)

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