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The continuous helical structure adopted by Retatrutide is crucial for its ability to penetrate the receptor transmembrane domain core via its amino-terminal segment while facilitating interactions with the extracellular domains through its carboxyl-terminal region [2] [8]

doi: 10.1007/s10787-019-00666-6 261 HuXTangJHuXBaoPDengWWuJet al

Neuropsychopharmacology 45 , 451461 (2020)

10.1016/j.tins.2005.02.001 325 ZoellerR

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