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Mediation of androgen metabolism by an optimal concentration of nicotine and serial concentrations of glutathione in cultured gingival and periosteal fibroblasts Incubations were performed with 6 cell-lines of fibroblasts in Eagle's MEM, using 14C-testosterone/14C-4-androstenedione as substrates with an effective concentration of nicotine established previously (N 250 g/ml), in the presence or absence of serial concentrations of glutathione (G, 14 g/ml)

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