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This article gives an overview on the clinical use of DPP-4 inhibitors

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Despite the potential of GLP-1RA plus SGLT2i combination therapy to improve metabolic-cardiovascular-renal trajectories, several factors may delay this combination to become a common practice soon, and most T2DM patients with ASCVD or at high ASCVD risk remain inadequately managed

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As expected things were a little wonky what the curves should look like is shown in the black line at the back

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References Okamoto A, Yokokawa H, Nagamine T, Fukuda H, Hisaoka T, Naito T

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