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You should not take either drug if you: Are under the age of 18 Are pregnant, breastfeeding, or planning to become pregnant Have kidney or liver disease Have a known allergy to either medication Additionally, both Zepbound and Ozempic carry a black box warning about an increased risk for thyroid C-cell tumors because these drugs caused thyroid tumors in rats in studies
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According to the Wegovy Summary of Product Characteristics (SmPC), injection site reactions are reported as 'common' (affecting between 1 in 10 and 1 in 100 people), while hypersensitivity reactions including urticaria are classified as 'uncommon' (affecting between 1 in 100 and 1 in 1,000 people)
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McDonald et al
Frontiers in Physiology , 11
