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Gastrointestinal side effects were mostly mild to moderate and linked to TZP, occurring mainly during dose escalation

The relationship between lactate and cancer growth reflects the pleotropic actions of this molecule able to influence the metabolic phenotype of the cancer cells

Glutathione is essential for numerous biological functions, with its antioxidant role being the most prominent

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Due to the advancements of neurological studies, brain function can be evaluated by monitoring dynamic changes of cerebral blood flow according to neurovascular coupling theory, i.e., neurons, astrocyte, and arterial vessel communication 39,40,41