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The Wnt/-catenin pathway is vital for osteogenic differentiation and bone formation (Grigorie & Lerner 2018)

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From an oxygen transport point of view, the Embden-Meyerhof pathway serves principally the generation of 2,3-BPG, because in terms of quantity, it is the principal glycolytic intermediate: the concentration of 2,3-BPG is about equal to the sum of all other glycolytic intermediates