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As a result, altered intracellular glutathione homeostasis has been widely used as an indicator of oxidative stress

Another open-label, randomized phase III inferiority study looked at mean A1c reduction in type 2 diabetics not controlled on metformin when treated with semaglutide or tirzepatide and tirzepatide was again found non-inferior (and even superior) in reducing A1c

For nausea, antiemetics may provide short-term relief but should be used under healthcare professional guidance

However, GLP-1 has a very short half-life [5]

There are some common physical side effects of Ozempic, like nausea, vomiting, constipation, and diarrhea, but there are some emotional and behavioral side effects as well

doi: 10.1016/j.bbamcr.2016.01.023 42 LucianiM.MuellerD.VanettaC.DiteepengT.Von EckardsteinA.AeschbacherS.et al