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Elsewhere on the internet I have read about research into the efficacy of Acetyl L-Carnitine and R-Lipoic Acid in enhancing the mitochondria function in rats, resulting in old rats performing like much younger rats
That is, the ADA recommends that one of these agents be considered as add-on therapy irrespective of the need for glucose lowering
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PMID 22117827
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Then, changes in their expression or activity may explain the ineffectiveness of some treatments and it may be exploited to improve the delivery of drugs also in the form of carnitine-derivatives
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