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Clinical trials showed Mounjaro (tirzepatide) produces 22.5% average weight loss compared to Ozempics (semaglutide) 14.9%
New England Journal of Medicine, 348(18), 1786-1795
In addition, preclinical evidence on GLP-1 effects in directly modulating the hypothalamuspituitarygonadal (HPG) axis, or the effects of GLP-1RA on clinical and biochemical expression of hyperandrogenism, concern new aspects in PCOS which are probably not always related to weight loss
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