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Comparative metabolic designs often pair Retatrutide with a single- or dual-agonist reference, or with an adjacent compound like MOTS-c, to attribute effects to specific mechanisms
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The most commonly reported effects include dry mouth, mild insomnia, and slight increases in heart rate and blood pressure
Other rare side effects include pancreatitis, gallbladder issues, low blood sugar and kidney problems
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In early March, the Food and Drug Administration expanded the approval of Wegovy to say the drug can be used to reduce the risk of cardiovascular death, heart attack and stroke in people with cardiovascular disease and either overweight or obesity
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